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Shuyi Si Selected Research

Lipids

2/2024A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue.
1/2020Rutaecarpine derivative R3 attenuates atherosclerosis via inhibiting NLRP3 inflammasome-related inflammation and modulating cholesterol transport.
11/2011Mycophenolic acid induces ATP-binding cassette transporter A1 (ABCA1) expression through the PPARγ-LXRα-ABCA1 pathway.
12/2010How can high-throughput screening deliver drugs to treat atherosclerosis?
8/2008Identification of upregulators of human ATP-binding cassette transporter A1 via high-throughput screening of a synthetic and natural compound library.

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Shuyi Si Research Topics

Disease

17Atherosclerosis
02/2024 - 03/2007
10Neoplasms (Cancer)
03/2024 - 08/2007
7Inflammation (Inflammations)
04/2024 - 01/2017
5Tuberculosis (Tuberculoses)
01/2021 - 01/2014
4COVID-19
03/2024 - 12/2021
4Infections
02/2021 - 09/2014
3Bacterial Infections (Bacterial Infection)
04/2019 - 01/2017
3Hepatocellular Carcinoma (Hepatoma)
05/2009 - 12/2004
2Dyslipidemias (Dyslipidemia)
02/2024 - 06/2023
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2022 - 01/2022
2Osteoporosis
11/2021 - 08/2016
2Cardiovascular Diseases (Cardiovascular Disease)
02/2020 - 01/2018
2Atherosclerotic Plaque (Atheroma)
01/2020 - 01/2018
1Genomic Instability
04/2024
1Necrosis
04/2024
1Bone Resorption
04/2024
1Lung Neoplasms (Lung Cancer)
03/2024
1Urinary Bladder Neoplasms (Bladder Cancer)
03/2024
1Hyperglycemia
02/2024
1Hypertrophy
02/2024
1Non-alcoholic Fatty Liver Disease
06/2023
1Body Weight (Weight, Body)
06/2023
1Carcinogenesis
01/2023
1Coronavirus Infections
01/2023
1Extensively Drug-Resistant Tuberculosis
11/2022
1Myeloperoxidase Deficiency
01/2021
1Chronic Disease (Chronic Diseases)
01/2020
1Mycoses (Diseases, Fungus)
08/2019
1Cachexia
01/2019
1Muscular Atrophy (Muscle Atrophy)
01/2019

Drug/Important Bio-Agent (IBA)

12CholesterolIBA
02/2024 - 08/2008
7Proteins (Proteins, Gene)FDA Link
04/2024 - 01/2019
7Apolipoproteins E (ApoE)IBA
02/2024 - 08/2014
5LipidsIBA
02/2024 - 08/2008
4Antiviral Agents (Antivirals)IBA
01/2023 - 07/2015
3LigandsIBA
04/2024 - 08/2016
3DNA (Deoxyribonucleic Acid)IBA
03/2024 - 04/2013
3Triglycerides (Triacylglycerol)IBA
02/2024 - 01/2018
3Sirtuin 1IBA
06/2023 - 01/2018
3Anti-Bacterial Agents (Antibiotics)IBA
01/2020 - 09/2014
3rutecarpineIBA
01/2020 - 08/2014
3ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2018 - 08/2008
3Liver X ReceptorsIBA
05/2016 - 04/2014
3norharmanIBA
01/2012 - 08/2007
2trichostatin A (A 300)IBA
03/2024 - 05/2009
2Cathepsin LIBA
03/2024 - 01/2023
2E1231IBA
06/2023 - 01/2018
2Small Interfering RNA (siRNA)IBA
11/2022 - 11/2017
2Anti-Infective Agents (Microbicides)IBA
11/2022 - 09/2018
2OsteoprotegerinIBA
11/2021 - 08/2016
2norvancomycinIBA
02/2021 - 01/2017
2Glucose (Dextrose)FDA LinkGeneric
02/2020 - 04/2015
2LuciferasesIBA
01/2017 - 08/2008
2Phospholipids (Phosphatides)FDA LinkGeneric
11/2011 - 08/2008
2Apolipoprotein A-I (Apolipoprotein A1)IBA
11/2011 - 08/2008
1Phosphotransferases (Kinase)IBA
04/2024
1SirtuinsIBA
04/2024
1CaspasesIBA
04/2024
1Acetaminophen (Paracetamol)FDA LinkGeneric
04/2024
1Actins (F Actin)IBA
04/2024
1Histone Deacetylase InhibitorsIBA
03/2024
1trichostatin CIBA
03/2024
1trans-sodium crocetinate (crocetin)IBA
03/2024
1DecitabineFDA Link
03/2024
1Antineoplastic Agents (Antineoplastics)IBA
03/2024
1MethyltransferasesIBA
03/2024
1Histone Deacetylases (Histone Deacetylase)IBA
03/2024
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
02/2024
1Blood Glucose (Blood Sugar)IBA
02/2024
1SARS-CoV-2 spike proteinIBA
01/2024
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
06/2023
1Alanine Transaminase (SGPT)IBA
06/2023
1Eosine Yellowish-(YS) (Eosin)IBA
06/2023
1Hematoxylin (Haematoxylon)IBA
06/2023
1nasIBA
06/2023
1oil red OIBA
06/2023
1EnzymesIBA
01/2023
1Peptide Hydrolases (Proteases)FDA Link
01/2023
1Interleukin-1beta (Interleukin 1 beta)IBA
11/2022
1NLR ProteinsIBA
11/2022
1Caspase 1 (ICE Protease)IBA
11/2022
1trichostatin DIBA
11/2022
1Clofazimine (Lamprene)FDA Link
11/2022
1T0901317IBA
01/2022
1RNA Splicing FactorsIBA
01/2022
1Cysteine (L-Cysteine)FDA Link
01/2022
1LipopolysaccharidesIBA
01/2022
1Messenger RNA (mRNA)IBA
01/2022
1DeoxyuridineIBA
01/2021
1dUTP pyrophosphataseIBA
01/2021
1Mitogen-Activated Protein KinasesIBA
01/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021
1tempolIBA
01/2021
1AntioxidantsIBA
01/2020
1oxidized low density lipoproteinIBA
01/2020
1InflammasomesIBA
01/2020
1Antifungal AgentsIBA
08/2019
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019

Therapy/Procedure

5Therapeutics
03/2024 - 08/2008
1Oral Administration
01/2023